By Gary M. White, MD
Hypereosinophilic Syndrome in an elderly woman.
Hypereosinophilic Syndrome (HES) is a systemic disorder featuring peripheral eosinophilia and eosinophilic infiltration of numerous organs, including the heart, lungs, skin, kidneys, liver, GI tract and nervous system.
Clinical
Cutaneous lesions occur in about half of patients. The most common findings are pruritic erythematous papules. Vesicobulla, diffuse eczema, nodules, erythroderma, EAC, pruritus, persistent mucosal erosions and vasculitis have all been reported.
Diagnosis
Criteria...